Pariah focuses on a robust immersive storyline that weaves survival elements into the traditional run-and-gun style of first-person action games.

Jack Mason is a burned-out doctor with no will to live, that is, until he nearly dies in a transport crash. Now he and his infected patient are stranded deep within the most vicious prison sectors of a wasteland called 'Earth'. In sixteen hours an orbital platform will initiate a total biohazard containment procedure: 50-megaton yield, detonated above sea level, to cleanse the contamination.